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Core Technology
3.Reversible hirudin
Source: | Author:pro954f45 | Published time: 2018-10-17 | 134 Views | Share:
    The invention provides a class of reversible hirudin, which is characterized by the modification and mutation of the amino acid of wild-type hirudin, and the transformed hirudin mutant can be reversed by thrombin enzymolysis after binding with thrombin, and gradually lose the function of inhibiting thrombin activity. At the same time, this class of reversible hirudin can be used to prepare anticoagulant drugs.